The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2016

Filed:

Nov. 26, 2013
Applicant:

Tyrx Pharma, Inc., Monmouth Junction, NJ (US);

Inventors:

Arthur Schwartz, East Windsor, NJ (US);

Satish Pulapura, Bridgewater, NJ (US);

Sarita Nethula, Monmouth Junction, NJ (US);

Assignee:

TYRX, INC., Monmouth Junction, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/10 (2006.01); A61L 31/10 (2006.01); A61L 31/04 (2006.01); A61L 31/14 (2006.01); C08G 63/685 (2006.01); C08G 64/12 (2006.01);
U.S. Cl.
CPC ...
A61L 31/10 (2013.01); A61L 31/041 (2013.01); A61L 31/148 (2013.01); C08G 63/6856 (2013.01); C08G 64/12 (2013.01);
Abstract

The present invention relates to polymers modified to increase their resorbability. In particular, the polymers of the invention have phenyl ester side chains which are good leaving groups and which thereby increase the resorption rate of the polymer relative to the same polymer, for example, bearing a comparable amount of an alkyl ester side chain. Such polymers are generally water insoluble, but when modified are able to solubilize drugs and upon degradation and resorption, release those in a physiological environment in a controlled and/or sustained manner.


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