The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2016
Filed:
Nov. 21, 2012
Applicants:
Julianto Setiady, Waltham, MA (US);
Peter U. Park, Somerville, MA (US);
Thomas Chittenden, Sudbury, MA (US);
Inventors:
Julianto Setiady, Waltham, MA (US);
Peter U. Park, Somerville, MA (US);
Thomas Chittenden, Sudbury, MA (US);
Assignee:
ImmunoGen, Inc., Waltham, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 31/395 (2006.01); C07K 16/30 (2006.01); A61K 47/48 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48369 (2013.01); A61K 39/39558 (2013.01); A61K 47/48384 (2013.01); A61K 47/48569 (2013.01); C07K 16/2863 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01);
Abstract
The present invention relates to the identification that EGFR antibody immunoconjugates are effective in inhibiting the growth of tumor cells that have developed EGFR and/or ALK resistance mechanisms. Methods of administering the EGFR antibody immunoconjugates to patients having resistant tumor cells is also disclosed.