The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2016
Filed:
Dec. 28, 2011
Ivan Alferiev, Clementon, NJ (US);
Michael Chorny, Huntingdon Valley, PA (US);
Robert J. Levy, Merion Station, PA (US);
Ivan Alferiev, Clementon, NJ (US);
Michael Chorny, Huntingdon Valley, PA (US);
Robert J. Levy, Merion Station, PA (US);
The Children's Hospital of Philadelphia, Philadelphia, PA (US);
Abstract
A prodrug according to formula (I) wherein Ris a residue of a drug, said drug having a hydroxyl group by which the COORgroup is formed; Z is O or NH; m is 0 or 1; and Ris an organic moiety comprising a lipophilic group or a residue of a polymer, provided that Z is 0 if the polymer is carboxymethyl dextran. A system includes a plurality of magnetic nanoparticles including a prodrug as described above, a stent and a source of uniform magnetic field capable of producing temporary magnetization of the stent and/or the magnetic nanoparticles. A method of treating a medical condition with a drug includes administering to a patient in need of the drug a prodrug as described above, the prodrug being capable of releasing the drug in the patient after the administration step.