The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2016

Filed:

Nov. 06, 2013
Applicant:

Catholic University Industry Academic Cooperation Foundation, Seoul, KR;

Inventors:

Jin Hee Shin, Seoul, KR;

Kyung Soo Kim, Seoul, KR;

Il Kyu Lee, Seoul, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61K 31/122 (2006.01); A61K 31/343 (2006.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 31/343 (2013.01); C12N 5/0654 (2013.01); C12N 2501/999 (2013.01); C12N 2506/1384 (2013.01);
Abstract

Provided are a composition for stimulating differentiation of MSCs into osteoblasts, which includes cryptotanshinone, and an osteogenesis stimulator including cryptotanshinone and MSCs. When the cryptotanshinone is treated to the MSCs, the differentiation into osteoblasts is stimulated, and thus osteogenesis of a patient may be stimulated by directly transplanting the differentiation-induced MSCs to the patient. Accordingly, the composition or osteogenesis stimulator may be used to treat patients having disability requiring stimulation of osteogenesis such as osteoporosis, bone fracture, bone grafting including alveolar bone grafting for implant placement, or other bone defects.


Find Patent Forward Citations

Loading…