The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2016

Filed:

Jul. 07, 2012
Applicants:

Richard Heng, Hegenheim, FR;

Elizabeth Kate Hoegenauer, Oberwil, CH;

Guido Koch, Bettingen, CH;

Robert Alexander Pulz, Basel, CH;

Anna Vulpetti, Basel, CH;

Rudolf Waelchli, Basel, CH;

Inventors:

Richard Heng, Hegenheim, FR;

Elizabeth Kate Hoegenauer, Oberwil, CH;

Guido Koch, Bettingen, CH;

Robert Alexander Pulz, Basel, CH;

Anna Vulpetti, Basel, CH;

Rudolf Waelchli, Basel, CH;

Assignee:

NOVARTIS AG, Basel, CH;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention describes new pyrrolo pyrimidine derivatives and pharmaceutically acceptable salts thereof which appear to interact with Bruton's tyrosine kinase (Btk). Accordingly, the novel pyrrolo pyrimidines may be effective in the treatment of autoimmune disorders, inflammatory diseases, allergic diseases, airway diseases, such as asthma and chronic obstructive pulmonary disease (COPD), transplant rejection, cancers e.g. of hematopoietic origin or solid tumors.


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