The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 2016

Filed:

Feb. 24, 2012
Applicants:

Omathanu P. Perumal, Brookings, SD (US);

Ranjith Kumar Averineni, Brookings, SD (US);

Satheesh K. Podaralla, Santa Clara, CA (US);

Mohammed Alqahtani, Brookings, SD (US);

Inventors:

Omathanu P. Perumal, Brookings, SD (US);

Ranjith Kumar Averineni, Brookings, SD (US);

Satheesh K. Podaralla, Santa Clara, CA (US);

Mohammed Alqahtani, Brookings, SD (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); A61K 31/07 (2006.01); A61K 35/12 (2015.01); A61K 35/16 (2015.01); C12N 15/87 (2006.01); A61K 8/49 (2006.01); A61K 8/64 (2006.01); A61Q 7/00 (2006.01); A61K 8/67 (2006.01); A61Q 19/00 (2006.01); A61K 8/98 (2006.01); A61K 8/02 (2006.01); A61K 9/00 (2006.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
A61K 31/505 (2013.01); A61K 8/0241 (2013.01); A61K 8/4953 (2013.01); A61K 8/64 (2013.01); A61K 8/671 (2013.01); A61K 8/983 (2013.01); A61K 9/0014 (2013.01); A61K 9/5169 (2013.01); A61K 31/07 (2013.01); A61K 35/12 (2013.01); A61K 35/16 (2013.01); A61Q 7/00 (2013.01); A61Q 19/00 (2013.01); C12N 15/87 (2013.01); A61K 2800/412 (2013.01); Y10T 428/13 (2015.01);
Abstract

The invention encompasses nanoparticle assemblies and methods for preparing nanoparticle and compositions comprising such nanoparticles for use in topical or skin applications. The invention further encompasses methods of complexing various molecular and cellular entities to the nanoparticles using the resulting nanoparticles of the invention as delivery devices. The nanoparticles can be used for a variety of applications, such as treating cancer, targeting tumors, reducing the toxicity of a drug in vivo, increasing the efficacy of a complexed agent in vivo, protecting a complexed agent against degradation, increasing skin penetration and retention of drugs, and enhancing the water solubility/dispersibility of a drug or other agent.


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