The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2016
Filed:
Sep. 13, 2008
Applicants:
Leonid Gorelik, Quincy, MA (US);
Margot Brickelmaier, Boxford, MA (US);
Alexey Lugovskoy, Woburn, MA (US);
Inventors:
Leonid Gorelik, Quincy, MA (US);
Margot Brickelmaier, Boxford, MA (US);
Alexey Lugovskoy, Woburn, MA (US);
Assignee:
Biogen MA Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 31/4709 (2006.01); A61K 31/47 (2006.01); A61K 45/06 (2006.01); A61K 31/196 (2006.01); A61K 31/352 (2006.01); A61K 31/437 (2006.01); A61K 31/44 (2006.01); A61K 31/554 (2006.01); A61K 31/573 (2006.01); A61K 31/575 (2006.01); A61K 31/58 (2006.01); A61K 31/69 (2006.01); A61K 31/7048 (2006.01); A61K 38/12 (2006.01); A61K 39/395 (2006.01); A61M 1/38 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4709 (2013.01); A61K 31/196 (2013.01); A61K 31/352 (2013.01); A61K 31/437 (2013.01); A61K 31/44 (2013.01); A61K 31/47 (2013.01); A61K 31/554 (2013.01); A61K 31/573 (2013.01); A61K 31/575 (2013.01); A61K 31/58 (2013.01); A61K 31/69 (2013.01); A61K 31/7048 (2013.01); A61K 38/12 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61M 1/38 (2013.01);
Abstract
The invention relates to compositions, methods, and kits for treating subjects infected by or at risk of infection with a DNA virus (e.g., a JC Virus or a BK virus). Aspects of the invention are useful to prevent or treat DNA virus associated conditions (e.g., PML) in subjects that are immunocompromised. Compositions are provided that inhibit intracellular replication of DNA viruses.