The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2016
Filed:
Oct. 12, 2012
Massachusetts Institute of Technology, Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Frank Alexis, Greenville, SC (US);
Matteo Iannacone, Milan, IT;
Jinjun Shi, Boston, MA (US);
Pamela Basto, Cambridge, MA (US);
Elliott Ashley Moseman, Jamaica Plain, MA (US);
Ulrich von Andrian, Chestnut Hill, MA (US);
Robert S. Langer, Newton, MA (US);
Omid C. Farokhzad, Waban, MA (US);
Elena Tonti, Riccione, IT;
Massachusetts Institute of Technology, Cambridge, MA (US);
The Brigham and Women's Hosptial, Inc., Boston, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface and an immunostimulatory moiety. In some embodiments, the immunostimulatory moiety is an adjuvant. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof.