The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2016
Filed:
Feb. 04, 2015
Applicant:
Cambrex Iep Gmbh, Wiesbaden, DE;
Inventors:
Assignee:
CAMBREX IEP GMBH, Wiesbaden, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/62 (2006.01); C12P 41/00 (2006.01); C12N 9/02 (2006.01); C12P 13/00 (2006.01);
U.S. Cl.
CPC ...
C12P 13/002 (2013.01); C12P 7/62 (2013.01); C12P 41/002 (2013.01); C12N 9/0008 (2013.01);
Abstract
In a process for the enantioselective enzymatic reduction of a hydroxy ketone of general formula I wherein R═C-Calkyl and R═—Cl, —CN, —OH, —H or C-Calkyl, into a chiral diol of general formula II wherein Rand Rhave the same meaning as in formula I, the hydroxy ketone is reduced with an oxidoreductase in the presence of NADH or NADPH as a cofactor, wherein