The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 2016

Filed:

Aug. 12, 2014
Applicant:

Takara Bio Inc., Otsu-shi, Shiga, JP;

Inventors:

Katsuyuki Dodo, Otsu, JP;

Naoki Saito, Otsu, JP;

Hideto Chono, Otsu, JP;

Junichi Mineno, Otsu, JP;

Assignee:

TAKARA BIO INC., Shiga, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 15/86 (2006.01); C12N 15/87 (2006.01); C12P 21/04 (2006.01); C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 2740/10043 (2013.01);
Abstract

Disclosed is a simple and highly efficient method for introducing a gene into a target cell using a retrovirus vector. The method comprises the steps of (a) placing a liquor containing a retrovirus vector having a foreign gene carried thereon into a bag for cell culture on which a retrovirus-binding substance has been immobilized, and incubating the liquor at a temperature lower than 25° C. for 8-48 hours, thereby producing a culture bag having the retrovirus vector bound thereto, (b) adding a target cell to the culture bag that has been produced in step (a) and incubating the culture bag for 8 hours or less, and (c) flipping the culture bag upside down and incubating the culture bag. The gene introduction method is useful particularly in medicine, cell technology, gene technology, and embryologic technology.


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