The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 2016

Filed:

Sep. 28, 2010
Applicants:

Young Chul Sung, Seoul, KR;

Sang Hoon Park, Anyang-si, KR;

Ki Seok Park, Pohang-si, KR;

Inventors:

Young Chul Sung, Seoul, KR;

Sang Hoon Park, Anyang-si, KR;

Ki Seok Park, Pohang-si, KR;

Assignees:

POSTECH ACADEMY-INDUSTRY FOUNDATION, Pohang-si, Gyeongsangbuk, KR;

BIOD CO., LTD., Pohang-si, Gyeongsangbuk, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C12N 15/63 (2006.01); C12N 15/864 (2006.01); C12N 15/861 (2006.01); C12N 15/867 (2006.01); C12N 15/00 (2006.01); C12N 15/863 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 15/63 (2013.01); C12N 15/00 (2013.01); C12N 15/861 (2013.01); C12N 15/863 (2013.01); C12N 15/864 (2013.01); C12N 15/867 (2013.01); C12N 15/8636 (2013.01); C12N 2710/10343 (2013.01); C12N 2710/10345 (2013.01); C12N 2810/10 (2013.01);
Abstract

The present invention relates to an intracellular viral vector delivery method employing an iron ion/viral vector composite. The iron ion/viral vector composite according to the present invention is not dependent on the expression of CAR and so improves the efficiency of delivery of viral vectors and gene expression in cells of diverse types, and has an outstanding virus-neutralizing antibody escape performance, exhibits little cytotoxicity and is outstandingly stable even when subjected to iron ion processing at low concentration, and hence can be used to advantage in recombinant viral vaccine compositions.


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