The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2016
Filed:
Mar. 15, 2013
Applicant:
Dynavax Technologies Corporation, Berkeley, CA (US);
Inventors:
Cristiana Guiducci, Albany, CA (US);
Karen L. Fearon, Lafayette, CA (US);
Franck Barrat, New York, NY (US);
Assignee:
Dynavax Technologies Corporation, Berkeley, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/117 (2010.01); A61K 31/7115 (2006.01); A61K 31/712 (2006.01); C07H 21/04 (2006.01); C07H 21/02 (2006.01); A61K 31/711 (2006.01); A61K 31/7125 (2006.01); A61K 31/713 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); C12N 15/117 (2013.01); A61K 31/711 (2013.01); A61K 31/712 (2013.01); A61K 31/713 (2013.01); A61K 31/7115 (2013.01); A61K 31/7125 (2013.01); C12N 2310/17 (2013.01); C12N 2310/331 (2013.01); C12N 2310/344 (2013.01);
Abstract
Provided herein are human Toll-like receptor (TLR)-inhibitors and methods for use in individuals having an autoimmune disease or an inflammatory disorder. The TLR inhibitors of the present disclosure are polynucleotides comprising an inhibitory motif for one or more of TLR7, TLR8 and TLR9.