The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2016
Filed:
Oct. 03, 2011
Applicants:
Christian Rohlff, Abingdon, GB;
Alasdair Stamps, Abingdon, GB;
Jonathan Alexander Terrett, San Jose, CA (US);
Inventors:
Christian Rohlff, Abingdon, GB;
Alasdair Stamps, Abingdon, GB;
Jonathan Alexander Terrett, San Jose, CA (US);
Assignee:
Oxford Biotherapeutics Ltd., Abington, Oxon, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61P 35/00 (2006.01); C07K 16/40 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); C07K 16/005 (2013.01); C07K 16/2803 (2013.01); C07K 2317/24 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/73 (2013.01); C07K 2317/77 (2013.01);
Abstract
The invention provides antibodies which bind to the extracellular domain of the Tyrosine-protein kinase transmembrane receptor ROR1. Nucleic acid molecules encoding the antibodies, expression vectors, host cells and methods for expressing the antibodies are also provided. The antibodies may be used for the treatment of cancer, including non-small cell lung carcinoma, B-cell chronic lymphocytic leukemia and colon cancer.