The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 2016

Filed:

Feb. 28, 2013
Applicant:

Novo Nordisk A/s, Bagsvaerd, DK;

Inventors:

Ida Hilden, Vanloese, DK;

Jes Thorn Clausen, Hoeng, DK;

Lars Christian Petersen, Hoersholm, DK;

Brit Binow Soerensen, Birkeroed, DK;

Helle Heibroch Petersen, Koebenhavn, DK;

Anders Svensson, Malmoe, SE;

Assignee:

Novo Nordisk A/S, Bagsvaerd, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/38 (2006.01);
U.S. Cl.
CPC ...
C07K 16/38 (2013.01); C07K 2317/34 (2013.01); C07K 2317/76 (2013.01);
Abstract

The invention relates to antibodies that are capable of specifically binding tissue factor pathway inhibitor (TFPI), neutralizing free TFPI and reducing the clotting time of blood. Furthermore, the invention relates to polynucleotides that encode such antibodies and to cells that comprise the polynucleotides or that express the antibodies of the invention. Such antibodies have utility in the treatment of subjects with a coagulopathy, alone as well as in combination with a second agent.


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