The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2016
Filed:
Dec. 17, 2013
Applicant:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Inventors:
Helen Blackwell, Middleton, WI (US);
Yftah Tal-Gan, Madison, WI (US);
Danielle Stacy, San Diego, CA (US);
Assignee:
WISCONSIN ALUMNI RESEARCH FOUNDATION, Madison, WI (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/12 (2006.01); C07K 5/12 (2006.01); C07K 7/56 (2006.01); C07K 7/64 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/12 (2013.01); A61K 38/12 (2013.01); C07K 7/56 (2013.01); C07K 7/64 (2013.01); A61K 38/00 (2013.01);
Abstract
Compounds that affect quorum sensing (QS) inand relatedspecies (e.g.,). Compounds which modulate one or more of the four AgrC receptors ofspecies, particularly of. Modulation includes inhibition or activation of one or more of these four AgrC receptors. These compounds are useful for bacterial interference and are useful for treating bacterial infections, particularly staphylococcal infection. Treatment can include combination of one or more of the compounds of the invention in combination with one or more antibiotics.