The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2016
Filed:
Jul. 02, 2013
Applicant:
Abbvie Inc., North Chicago, IL (US);
Inventors:
Yi-Yin Ku, North Chicago, IL (US);
Steven Hannick, North Chicago, IL (US);
Ashok K. Gupta, Gurnee, IL (US);
Assignee:
AbbVie Inc., North Chicago, IL (US);
Primary Examiner:
Int. Cl.
CPC ...
C07C 233/23 (2006.01); C07C 49/755 (2006.01); C07C 49/697 (2006.01); C07C 233/59 (2006.01); C07C 233/60 (2006.01); C07C 231/12 (2006.01); C07D 207/24 (2006.01); C07C 231/14 (2006.01); C07C 233/14 (2006.01); C07D 207/38 (2006.01); C07C 233/06 (2006.01);
U.S. Cl.
CPC ...
C07C 49/755 (2013.01); C07C 49/697 (2013.01); C07C 231/12 (2013.01); C07C 231/14 (2013.01); C07C 233/06 (2013.01); C07C 233/14 (2013.01); C07C 233/23 (2013.01); C07C 233/59 (2013.01); C07C 233/60 (2013.01); C07D 207/24 (2013.01); C07D 207/38 (2013.01);
Abstract
The present invention provides a process for preparing a bicyclic amine derivative of the formula (Ia) or (Ib), comprising the rhodium-catalyzed asymmetric hydrogenation of an enamine of the formula (II), in the presence of a chiral ligand, wherein the chiral ligand is a chiral phosphine ligand.