The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 2016

Filed:

May. 31, 2012
Applicant:

Dan Hashimshony, Givat Ada, IL;

Inventor:

Dan Hashimshony, Givat Ada, IL;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61K 49/00 (2006.01); A61B 5/053 (2006.01); A61B 5/06 (2006.01);
U.S. Cl.
CPC ...
A61K 49/00 (2013.01); A61B 5/0075 (2013.01); A61B 5/0084 (2013.01); A61B 5/0538 (2013.01); A61B 5/411 (2013.01); A61B 5/416 (2013.01); A61B 5/0071 (2013.01); A61B 5/0091 (2013.01); A61B 5/065 (2013.01);
Abstract

A method, apparatus and probe for examining tissue for the presence of target cells, particularly cancerous cells, by subjecting the tissue to be examined to a contrast agent containing small particles of a physical element conjugated with a biological carrier selectively bindable to the target cells. Energy pulses are applied to the examined tissue. The changes in impedance and/or optical characteristics of the examined tissue produced by the applied energy pulses are detected and utilized for determining the presence of the target cells in the examined tissue. In a described preferred embodiment, the applied energy pulses include laser pulses, and the physical element conjugated with a biological carrier is a light-sensitive semiconductor having an impedance which substantially decreases in the presence of light. The same probe used for detecting the targeted cells may also be used for destroying the cells so targeted.


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