The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 2016
Filed:
Feb. 28, 2013
Henner Knust, Rheinfelden, DE;
Andreas Koblet, Bottmingen, CH;
Matthias Nettekoven, Grenzach-Wyhlen, DE;
Hasane Ratni, Habsheim, FR;
Claus Riemer, Freiburg, DE;
Walter Vifian, Gelterkinden, CH;
Henner Knust, Rheinfelden, DE;
Andreas Koblet, Bottmingen, CH;
Matthias Nettekoven, Grenzach-Wyhlen, DE;
Hasane Ratni, Habsheim, FR;
Claus Riemer, Freiburg, DE;
Walter Vifian, Gelterkinden, CH;
HOFFMANN-LA ROCHE INC., Nutley, NJ (US);
Abstract
The present invention relates to compounds of formula wherein R, R, R, R, Z, and n are as defined hereinor to a pharmaceutically active salt thereof. Compounds of the invention are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).