The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2015
Filed:
Mar. 12, 2009
Patrick Schweizer, Ballenstedt, DE;
Goetz Hensel, Koethen, DE;
Alexandra Gay, Odenthal, DE;
Jochen Kumlehn, Postdam, DE;
Patrick Schweizer, Ballenstedt, DE;
Goetz Hensel, Koethen, DE;
Alexandra Gay, Odenthal, DE;
Jochen Kumlehn, Postdam, DE;
The Leibniz Institute of Plant Genetics and Crop Plant Research, Gatersleben, DE;
Abstract
The present invention relates to the creation of broad-spectrum resistance in transgenic plants by inserting inhibitory nucleic acid sequences inhibiting the expression of fungal genes. The nucleic acid sequences of genes which are crucial to development, growth and profilation of fungi, i.e. sequences of genes with an essential function in fungi, are often conserved and/or have a high sequence identity. Regions having a particularly high sequence identity between various fungi are used in order to produce inhibitory gene constructs, e.g. on basis of antisense, siRNA, shRNA, ribozyme technology and other technologies imparting the inhibition of the expression and activation of genes. Since said methods base on the sequence-specific hybridization of the inhibitory RNA molecules with respective target sequences in certain fungal genes, the expression of all corresponding genes from various fungi is thus inhibited as well. Due to the high sequence identity of such conserved gene sections, transgenic plants are thus produced, which have broad-spectrum resistance to various fungi.