The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2015
Filed:
Sep. 23, 2010
Adam Judge, Vancouver, CA;
Yun-han Lee, Rockville, MD (US);
Ian Maclachlan, Mission, CA;
Snorri S. Thorgeirsson, Bethesda, MD (US);
Adam Judge, Vancouver, CA;
Yun-Han Lee, Rockville, MD (US);
Ian MacLachlan, Mission, CA;
Snorri S. Thorgeirsson, Bethesda, MD (US);
PROTIVA BIOTHERAPEUTICS, INC., Burnaby, BC, CA;
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, Bethesda, MD (US);
Abstract
The present invention provides therapeutic nucleic acids such as interfering RNA (e.g., siRNA) that target the expression of genes associated with tumorigenesis and/or cell transformation, lipid particles (e.g., nucleic acid-lipid particles) comprising one or more (e.g., a cocktail) of the therapeutic nucleic acids, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles, e.g., for the treatment of a cell proliferative disorder such as cancer.