The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2015
Filed:
May. 20, 2011
Applicants:
Arne Skerra, Freising, DE;
Uli Binder, Freising, DE;
Martin Schlapschy, Freising, DE;
Inventors:
Assignees:
Technische Universitat Munchen, Munich, DE;
XL-Protein GmbH, Freising, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); C07K 7/08 (2006.01);
U.S. Cl.
CPC ...
C07K 14/00 (2013.01); C07K 7/08 (2013.01); C07K 14/001 (2013.01);
Abstract
We discovered that a biosynthetic polypeptide, consisting of at least about 50 proline (Pro) and alanine (Ala) amino acid residues, forms a random coil, and increases the stability of other compounds to which it is conjugated, such as small molecules and polypeptides. We describe such biosynthetic polypeptides, constructs containing such polypeptides, ways of making them, and their use.