The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9221873 B1

PDF
Full Text
Expired
Date of Patent:
Dec. 29, 2015

Filed:

Sep. 24, 2014
Applicant:

National Taiwan University, Taipei, TW;

Inventors:

Chih-Hsien Chiu, Taipei, TW;

Meng-Chieh Hsu, Taipei, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); C07K 7/06 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 7/06 (2013.01); C07K 14/47 (2013.01); C07K 14/4705 (2013.01);
Abstract

A short-chain peptide capable of controlling spermatozoa fertilization performance is supplied in an in vitro culture medium of spermatozoa and oocytes to increase the success rates of in vitro fertilization. The short-chain peptide comprises an amino acid sequence H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-X-NH2 (SEQ ID NO: 1), where X denotes Tyr or Phe, and the sequence ends with an amide. The short-chain peptide is conducive to adjustment of the concentration of free calcium ions inside the cells of the spermatozoa and thus enhancement of the success rates of in vitro fertilization.


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Chiu, Chih-Hsien. (2015). Short-chain peptide capable of controlling spermatozoa fertilization performance (U.S. Patent No. 9221873). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9221873

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