The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2015
Filed:
Dec. 01, 2011
Applicants:
Bilha Fischer, Shoham, IL;
Jesus Jeronimo Pintor, Madrid, ES;
Shay Elyahu, Ramat-Efal, IL;
Tamar Ginsburg-shmuel, Ra'anana, IL;
Inventors:
Bilha Fischer, Shoham, IL;
Jesus Jeronimo Pintor, Madrid, ES;
Shay Elyahu, Ramat-Efal, IL;
Tamar Ginsburg-Shmuel, Ra'anana, IL;
Assignees:
BAR-ILAN UNIVERSITY, , IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/04 (2006.01); A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 23/00 (2006.01); C07F 9/6558 (2006.01); C07H 19/10 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
C07H 23/00 (2013.01); C07F 9/65586 (2013.01); C07H 19/10 (2013.01); C07H 21/02 (2013.01);
Abstract
The disclosure provides particular uridine di- and tri-phosphate compounds of Formula I, and pharmaceutical compositions thereof. The definitions of variables such as R, Y, B, m, Z, Z, and Zare as provided in the disclosure. These compounds are useful for treatment of diseases, disorders and conditions modulated by P2Yreceptors, and particularly for lowering intraocular pressure and thereby treating ocular hypertension and/or glaucoma.