The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2015

Filed:

Aug. 28, 2014
Applicant:

Epitherapeutics Aps, Københaven N, DK;

Inventors:

Marc Labelle, Basking Ridge, NJ (US);

Thomas Boesen, København Ø, DK;

Qasim Khan, Winnipeg, CA;

Ramkrishna Reddy Vakiti, Winnipeg, CA;

Utpal Sharma, Brampton, CA;

Ying Yang, Winnipeg, CA;

Mukund Mehrotra, Winnipeg, CA;

Neerja Saraswat, Winnipeg, CA;

Farman Ullah, Winnipeg, CA;

Assignee:

Epitherapeutics APS, Copenhagen N, DK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/04 (2006.01); C07D 213/56 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 213/38 (2006.01); C07D 213/48 (2006.01); C07C 55/06 (2006.01); C07C 309/30 (2006.01);
U.S. Cl.
CPC ...
C07D 413/04 (2013.01); C07C 55/06 (2013.01); C07C 309/30 (2013.01); C07D 213/38 (2013.01); C07D 213/48 (2013.01); C07D 213/56 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01);
Abstract

Compounds of the form In which Q is selected from —CH═NR, —W, —CHNHR, —CH═O and —CH(OR)capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer and formulations and methods of use of such compounds.


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