The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2015

Filed:

Sep. 05, 2011
Applicants:

Yili Ding, Shanghai, CN;

Xuan Yang, Shanghai, CN;

Qingyan Yan, Shanghai, CN;

Hua Bai, Zhejiang, CN;

Lifeng Cai, Shanghai, CN;

Kenneth Smith, Shanghai, CN;

Jian Chai, Zhejiang, CN;

Inventors:

Yili Ding, Shanghai, CN;

Xuan Yang, Shanghai, CN;

Qingyan Yan, Shanghai, CN;

Hua Bai, Zhejiang, CN;

Lifeng Cai, Shanghai, CN;

Kenneth Smith, Shanghai, CN;

Jian Chai, Zhejiang, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 403/12 (2006.01); A61K 31/4155 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/4155 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01);
Abstract

Provided are derivatives substituted by urea associated with 4-substituted-(3-substituted-1H-pyrazole-5-amino)-pyrimidine-2-amino of formula (I), wherein these compounds may selectively regulate or inhibit an information transmission process controlled by natural or variant tyrosine kinase. Also provided are preparation methods and uses of the compounds.


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