The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2015

Filed:

Dec. 06, 2012
Applicant:

Ltt Bio-pharma Co., Ltd., Minato-ku, Tokyo, JP;

Inventors:

Toru Mizushima, Tokyo, JP;

Masami Otsuka, Tokyo, JP;

Yoshinari Okamoto, Tokyo, JP;

Naoki Yamakawa, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 333/24 (2006.01); C07D 307/54 (2006.01); C07C 205/56 (2006.01); C07C 309/65 (2006.01); C07C 323/62 (2006.01); C07C 229/42 (2006.01); C07C 69/65 (2006.01); C07C 69/732 (2006.01); C07C 69/757 (2006.01); C07C 59/215 (2006.01); C07C 69/67 (2006.01); C07C 59/72 (2006.01); C07C 59/88 (2006.01); C07C 59/90 (2006.01);
U.S. Cl.
CPC ...
C07D 333/24 (2013.01); C07C 59/215 (2013.01); C07C 59/72 (2013.01); C07C 59/88 (2013.01); C07C 59/90 (2013.01); C07C 69/65 (2013.01); C07C 69/67 (2013.01); C07C 69/732 (2013.01); C07C 69/757 (2013.01); C07C 205/56 (2013.01); C07C 229/42 (2013.01); C07C 309/65 (2013.01); C07C 323/62 (2013.01); C07D 307/54 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01);
Abstract

Provided are novel 2-fluorophenyl propionic acid derivatives which have excellent anti-inflammatory/analgesic effects while avoiding side effects such as gastrointestinal disorders, namely 2-fluorophenyl propionic acid derivatives represented by the formula (I) below or pharmaceutically acceptable salts thereof, [wherein, Rrepresents a hydrogen atom, a halogen atom, or a substituted or unsubstituted phenyl group, X represents —CH—, —NH—, —O—, or —S—, and Y specifically represents group (II) (wherein, Zrepresents —CO—, —CH(OH)—, or —CH—, and n represents an integer of 1 or 2.)]


Find Patent Forward Citations

Loading…