The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2015

Filed:

Aug. 20, 2014
Applicant:

Institute of Nuclear Energy Research Atomic Energy Council, Executive Yuan, Taoyuan County, TW;

Inventors:

Tsai-Yueh Luo, Taoyuan County, TW;

Te-Sheng Liang, Taoyuan County, TW;

Ying-Hsia Shih, Taoyuan County, TW;

Wuu-Jyh Lin, Taoyuan County, TW;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01J 19/24 (2006.01); B01J 19/00 (2006.01); A61K 51/04 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
B01J 19/0006 (2013.01); A61K 51/04 (2013.01); A61K 51/0406 (2013.01); B01J 19/00 (2013.01); B01J 19/0013 (2013.01); B01J 19/24 (2013.01); C07B 59/00 (2013.01); B01J 2219/00051 (2013.01); B01J 2219/00182 (2013.01);
Abstract

The present invention relates to an automatic system for synthesizing iodine-123 meta-iodobenzylguanidine (I-MIBG), which comprises a first reactor for subjecting radioactive iodine-containing sodium iodide and meta-iodobenzylguanidine (MIBG) sulfate to an iodine-iodine exchange reaction to obtain radioactive iodine labeled MIBG; a purification unit for purifying the iodine labeled MIBG; and a second reactor for substituting a solvent used in purification with a phosphate buffer to obtain a phosphate solution containingI-MIBG. The present invention also relates to an automatic device for dispensingI-MIBG, which comprises the automatic system for synthesizingI-MIBG, a radioactivity measuring unit, and a dispensing and packing unit.


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