The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2015

Filed:

Dec. 30, 2011
Applicants:

Sung-won Choi, Daejeon, KR;

Muhn-ho LA, Daejeon, KR;

Ji-yeon Son, Daejeon, KR;

Min-hyo Seo, Daejeon, KR;

Inventors:

Sung-Won Choi, Daejeon, KR;

Muhn-Ho La, Daejeon, KR;

Ji-Yeon Son, Daejeon, KR;

Min-Hyo Seo, Daejeon, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/16 (2006.01); A61K 31/7105 (2006.01); A61K 47/48 (2006.01); A61K 9/107 (2006.01); A61K 9/127 (2006.01); C12N 15/88 (2006.01); A61K 47/18 (2006.01); A61K 47/28 (2006.01);
U.S. Cl.
CPC ...
A61K 47/16 (2013.01); A61K 9/107 (2013.01); A61K 9/1075 (2013.01); A61K 9/1272 (2013.01); A61K 31/7105 (2013.01); A61K 47/48192 (2013.01); A61K 47/48207 (2013.01); C12N 15/88 (2013.01); A61K 47/18 (2013.01); A61K 47/28 (2013.01);
Abstract

Disclosed are a carrier for delivering a negatively charged drug, comprising a cationic lipid represented by formula 1, and a preparation method thereof. Also disclosed is a pharmaceutical composition comprising a negatively charged drug and a cationic lipid represented by formula 1, wherein the negatively charged drug forms a complex with the cationic lipid. The composition can increase the in vivo stability of the negatively charged drug after local or systemic administration and allows the intracellular delivery of the negatively charged drug. Thus, the composition will be useful for improving the therapeutic effect of the negatively charged drug.


Find Patent Forward Citations

Loading…