The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2015

Filed:

Aug. 26, 2010
Applicants:

Mark A. Suckow, Granger, IN (US);

William R. Wolter, Granger, IN (US);

Paul J. Hall, Lafayette, IN (US);

Inventors:

Mark A. Suckow, Granger, IN (US);

William R. Wolter, Granger, IN (US);

Paul J. Hall, Lafayette, IN (US);

Assignees:

The University of Notre Dame, Notre Dame, IN (US);

Cook Biotech, Inc., West Lafayette, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/39 (2006.01); A61K 39/00 (2006.01); A61K 39/08 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 39/08 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55588 (2013.01);
Abstract

Disclosed are vaccines and vaccine adjuvants useful in the treatment and/or prevention of infection and diseases associated with infectious pathogens, such as tetanus, as well as diseases associated with biological toxins. Also provided are methods of preparing an adjuvant and the vaccine containing the adjuvant. Methods are also provided for vaccinating/immunizing an animal against infection and diseases associated with infectious pathogens, such as tetanus, and other diseases associated with biological toxins. Adjuvant materials are presented that are prepared from an extracellular matrix material. The adjuvant may also be described as a heterologous acellular collagenous tissue preparation. The adjuvants are demonstrated to enhance the immunogencity of an infectious pathogen antigen or biological toxin antigen of interest, as well as to enhance the survival of an immunized animal.


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