The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2015

Filed:

Sep. 13, 2012
Applicants:

Sylvia Brunner, Vienna, AT;

Gergana Galabova, Vienna, AT;

Bettina Wanko, Vienna, AT;

Markus Windwarder, Gaenserndorf, AT;

Gabriele Winsauer, Vienna, AT;

Guenther Staffler, Vienna, AT;

Claudia Juno, Vienna, AT;

Inventors:

Sylvia Brunner, Vienna, AT;

Gergana Galabova, Vienna, AT;

Bettina Wanko, Vienna, AT;

Markus Windwarder, Gaenserndorf, AT;

Gabriele Winsauer, Vienna, AT;

Guenther Staffler, Vienna, AT;

Claudia Juno, Vienna, AT;

Assignee:

AFFIRIS AG, Vienna, AT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/39 (2006.01); C12N 9/64 (2006.01); C07K 16/40 (2006.01); A61K 39/385 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0005 (2013.01); A61K 39/0012 (2013.01); A61K 39/385 (2013.01); A61K 39/39 (2013.01); C07K 16/40 (2013.01); C12N 9/6454 (2013.01); A61K 2039/54 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/6081 (2013.01); C07K 2317/34 (2013.01); C07K 2319/00 (2013.01); C07K 2319/21 (2013.01); C07K 2319/23 (2013.01); C07K 2319/40 (2013.01); C07K 2319/50 (2013.01);
Abstract

A vaccine or immunogenic composition comprising at least two fragments of proprotein convertase subtilisin/kexin type 9 (PCSK9) where one fragment contains at least 9 consecutive residues of residues 153 to 165 of PCSK9 and the other fragment contains at least 9 consecutive residues 209 to 222 of the PCSK9 (SEQ ID NO:9). Methods of treatment for hyperlipidemia, hypercholesterolemia, and atherosclerosis involving administering this vaccine.


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