The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2015
Filed:
May. 21, 2007
Margaret A. Wheatley, Media, PA (US);
Odelia Mualem Burstein, Philadelphia, PA (US);
John R. Eisenbrey, Middletown, DE (US);
Dalia El-sherif, King of Prussia, PA (US);
Margaret A. Wheatley, Media, PA (US);
Odelia Mualem Burstein, Philadelphia, PA (US);
John R. Eisenbrey, Middletown, DE (US);
Dalia El-Sherif, King of Prussia, PA (US);
Drexel University, Philadelphia, PA (US);
Abstract
This invention provides an improvement to methods of drug loading of ultrasound contrast agents. Echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof produced by the method of the invention wherein the echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof contain at least 10% more of a drug as compared to (1) echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof prepared by adding drug prior to emulsifying or (2) echogenic drug-loaded polymer microcapsules, nanocapsules, or mixtures thereof prepared by adding drug to lyophilized polymer microcapsules, nanocapsules, or mixtures thereof.