The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 29, 2015

Filed:

Oct. 15, 2012
Applicant:

Hanmi Pharm Co., Ltd., Hwaseong-si, Gyeonggi-do, KR;

Inventors:

Kyeong Soo Kim, Suwon-si, KR;

Ki Young Jang, Suwon-si, KR;

Seung Jae Park, Seoul, KR;

Yong Il Kim, Suwon-si, KR;

Jae Hyun Park, Suwon-si, KR;

Jong Soo Woo, Suwon-si, KR;

Assignee:

HANMI PHARM. CO., LTD., Hwaseong-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/24 (2006.01); A61K 9/20 (2006.01); A61K 9/28 (2006.01); A61K 31/4178 (2006.01); A61K 31/4422 (2006.01); A61K 31/549 (2006.01); A61K 31/40 (2006.01); A61K 31/4418 (2006.01); A61K 31/4453 (2006.01); A61K 31/47 (2006.01); A61K 31/495 (2006.01); A61K 31/5415 (2006.01); A61K 31/616 (2006.01); A61K 9/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/24 (2013.01); A61K 9/205 (2013.01); A61K 9/2086 (2013.01); A61K 9/2866 (2013.01); A61K 9/4808 (2013.01); A61K 31/40 (2013.01); A61K 31/4178 (2013.01); A61K 31/4418 (2013.01); A61K 31/4422 (2013.01); A61K 31/4453 (2013.01); A61K 31/47 (2013.01); A61K 31/495 (2013.01); A61K 31/549 (2013.01); A61K 31/5415 (2013.01); A61K 31/616 (2013.01);
Abstract

The present invention relates to a hard capsule composite formulation comprising a capsule having a hemispherical closure at each end and an interior space; and one or more tablets encapsulated in the capsule, wherein the tablet or the tablets as a whole have a shape conforming to the internal space of the capsule. The hard capsule composite formulation can efficiently charge pharmaceutical compositions inside the limited interior space of the capsule, and hence, it allows packing a high-dose of pharmaceutical composition in a relatively small-sized capsule, which increases productivity and patient compliance. Also, the composite formulation exhibits good dissolution rate because pharmaceutically active ingredients contained in the capsule are separated from one another, and thus, the ingredients are less affected by the dissolution rate of one another, allowing good storage stability which can optimize the therapeutic effects.


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