The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 2015
Filed:
Apr. 21, 2010
Jennifer M. Munson, Atlanta, GA (US);
Ravi V. Bellamkonda, Marietta, GA (US);
Jack L. Arbiser, Atlanta, GA (US);
Jennifer M. Munson, Atlanta, GA (US);
Ravi V. Bellamkonda, Marietta, GA (US);
Jack L. Arbiser, Atlanta, GA (US);
Emory University, Atlanta, GA (US);
Georgia Tech Research Corporation, Atlanta, GA (US);
Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);
Abstract
Liposomes of a size of less than 200 nanometers target tumors and preferentially deliver imipramine blue to tumors, including brain tumors such as gliomas. The imipramine blue decreases the invasiveness of the tumors, and inhibits tumor metastasis. The liposomes include cholesterol and chemically pure phospholipids that are essentially neutral and contain saturated fatty acids of between 16 and 18 carbon atoms, such as distearoylphosphatidyl choline, and can also include one or more pegylated phospholipids, such as DSPE-PEG.