The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2015

Filed:

Apr. 13, 2012
Applicants:

David Jackson, Heidelberg, DE;

Theodoros Soldatos, Heidelberg, DE;

Guillaume Taglang, Heidelberg, DE;

Alexander Zien, Heidelberg, DE;

Stephan Brock, Heidelberg, DE;

Inventors:

David Jackson, Heidelberg, DE;

Theodoros Soldatos, Heidelberg, DE;

Guillaume Taglang, Heidelberg, DE;

Alexander Zien, Heidelberg, DE;

Stephan Brock, Heidelberg, DE;

Assignee:

MOLECULAR HEALTH GMBH, Heidelberg, DE;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); G06F 19/00 (2011.01); G06F 19/18 (2011.01);
U.S. Cl.
CPC ...
G06F 19/345 (2013.01); G06F 19/18 (2013.01); G06F 19/326 (2013.01); G06F 19/3437 (2013.01);
Abstract

The present disclosure is directed to systems and methods for identifying unknown drug targets via adverse event data. An analyzer receives an identification of a first drug having one or more unknown target proteins and identifies a second drug related to the first drug. The analyzer retrieves, from an adverse event database, a first side effect profile associated with the first drug, and a second side effect profile associated with the second drug. The analyzer generates a third side effect profile including a subset of the first side effect profile not shared by the second side effect profile, and identifies a third drug having a fourth side effect profile including the third side effect profile. The analyzer retrieves a list of one or more target proteins of the third drug not targeted by the second drug, and presents the retrieved list as potential target proteins of the first drug.


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