The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2015
Filed:
Oct. 18, 2010
Hiroshi Handa, Yokohama, JP;
Hideki Ando, Yokohama, JP;
Takumi Itoh, Yokohama, JP;
Kentaro Hotta, Yokohama, JP;
Hiroshi Handa, Yokohama, JP;
Hideki Ando, Yokohama, JP;
Takumi Itoh, Yokohama, JP;
Kentaro Hotta, Yokohama, JP;
Tokyo Institute of Technology, Tokyo, JP;
Fujimoto Pharmaceutical Corporation, Osaka, JP;
Abstract
With an aim to provide means for developing a compound devoid of teratogenicity but retaining beneficial actions, a screening method for a non-teratogenic substance comprising bringing a test substance into contact with cereblon or a fragment of cereblon, evaluating the bindability of the test substance with cereblon or the fragment of cereblon, and selecting a test substance that does not bind to cereblon or the fragment of cereblon or a test substance exhibiting lower bindability with cereblon or the fragment of cereblon than does thalidomide is provided.