The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2015
Filed:
Mar. 06, 2013
Applicant:
The Trustees of Columbia University IN the City of New York, New York, NY (US);
Inventors:
Jacob Rosenstein, New York, NY (US);
Kenneth L. Shepard, Ossining, NY (US);
Assignee:
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/447 (2006.01); B82Y 5/00 (2011.01); C12Q 1/68 (2006.01); B82Y 15/00 (2011.01); G01N 33/68 (2006.01); G01N 33/487 (2006.01);
U.S. Cl.
CPC ...
G01N 27/447 (2013.01); B82Y 5/00 (2013.01); B82Y 15/00 (2013.01); C12Q 1/6869 (2013.01); G01N 27/44791 (2013.01); G01N 33/48721 (2013.01); G01N 33/68 (2013.01); Y10S 977/852 (2013.01);
Abstract
A system and method for detecting a single-molecule using an integrated circuit which includes at least one membrane having a nanopore located between first and second reservoirs and a low-noise preamplifier having an electrode formed on the surface thereof is provided. The method includes passing a target molecule through the nanopore, and measuring a current through the nanopore to detect the presence of a biomolecular entity, if any.