The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2015

Filed:

Feb. 27, 2013
Applicant:

Helmholtz-zentrum Fuer Infektionsforschung Gmbh, Braunschweig, DE;

Inventors:

Rolf Mueller, Blieskastel, DE;

Silke Wenzel, Ahnatal, DE;

Ronald Garcia, Saarbruecken, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/02 (2006.01); C07K 7/56 (2006.01); C12N 15/52 (2006.01); C12P 17/16 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 9/22 (2006.01); C12N 9/88 (2006.01); C12N 15/74 (2006.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); C07K 7/56 (2013.01); C12N 9/0069 (2013.01); C12N 9/1007 (2013.01); C12N 9/22 (2013.01); C12N 9/88 (2013.01); C12N 15/52 (2013.01); C12N 15/74 (2013.01); C12P 17/167 (2013.01);
Abstract

The invention provides the amino acid sequences comprised in or constituting the synthetic pathway enzymes participating in the production of Argyrins, as well as the nucleic acid sequences encoding the synthetic pathway enzymes participating in the production of Argyrins, as well as genetically manipulated microorganisms containing nucleic acid sequences encoding the synthetic pathway enzymes for the production of Argyrins, e.g. for inserting one or more of these coding sequences, mutating in a targeted manner one or more of these nucleic acid sequences, in a wild type producer micro-organism or in a heterologous micro-organism, for the production of Argyrins.


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