The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2015

Filed:

Feb. 29, 2008
Applicants:

Jennifer A. Chaplin, San Diego, CA (US);

Ellen Chi, Del Mar, CA (US);

Grace Desantis, San Diego, CA (US);

Mark Madden, La Mesa, CA (US);

Darcy Madden, San Diego, CA (US);

Aileen Milan, San Diego, CA (US);

Dan E. Robertson, Belmont, MA (US);

Jay M. Short, Del Mar, CA (US);

David P. Weiner, Del Mar, CA (US);

Inventors:

Jennifer A. Chaplin, San Diego, CA (US);

Ellen Chi, Del Mar, CA (US);

Grace DeSantis, San Diego, CA (US);

Mark Madden, La Mesa, CA (US);

Aileen Milan, San Diego, CA (US);

Dan E. Robertson, Belmont, MA (US);

Jay M. Short, Del Mar, CA (US);

David P. Weiner, Del Mar, CA (US);

Assignee:

BASF Enzymes LLC, San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C07H 21/02 (2006.01); A61K 38/43 (2006.01); C12P 7/42 (2006.01); C12N 9/78 (2006.01); C12P 13/00 (2006.01); C12P 13/04 (2006.01); C12P 41/00 (2006.01);
U.S. Cl.
CPC ...
C12P 7/42 (2013.01); C12N 9/78 (2013.01); C12P 13/002 (2013.01); C12P 13/004 (2013.01); C12P 13/005 (2013.01); C12P 13/04 (2013.01); C12P 41/007 (2013.01);
Abstract

The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.


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