The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2015
Filed:
Apr. 13, 2012
Eric Ogier-denis, Paris, FR;
Xavier Treton, Paris, FR;
Fanny Daniel, Paris, FR;
Cecile Guichard, Paris, FR;
Eric Pedruzzi, Paris, FR;
Yoram Bouhnik, Paris, FR;
Yann Harnoy, Paris, FR;
Eric Ogier-Denis, Paris, FR;
Xavier Treton, Paris, FR;
Fanny Daniel, Paris, FR;
Cecile Guichard, Paris, FR;
Eric Pedruzzi, Paris, FR;
Yoram Bouhnik, Paris, FR;
Yann Harnoy, Paris, FR;
Abstract
The present invention relates to a non human model animal for ulcerative colitis and its main complications such as primary sclerosing cholangitis and colorectal cancer. More particularly, the present invention relates to a transgenic non human animal model for ulcerative colitis and its main complications such as primary sclerosing cholangitis, and colorectal cancer comprising a targeted disruption in the IL10 and NOX1 genes so that IL10 and NOX1 are not expressed in said animal.