The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2015

Filed:

Sep. 13, 2012
Applicants:

George R. Kracke, Columbia, MO (US);

Yulia Sevryugina, Columbia, MO (US);

Marion Frederick Hawthorne, Columbia, MO (US);

Inventors:

George R. Kracke, Columbia, MO (US);

Yulia Sevryugina, Columbia, MO (US);

Marion Frederick Hawthorne, Columbia, MO (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01); C07F 5/05 (2006.01);
U.S. Cl.
CPC ...
C07F 5/027 (2013.01); C07F 5/05 (2013.01);
Abstract

The present invention relates to novel cluster boron compounds and their use as sodium channel blockers. In particular, the novel cluster boron compounds may be lidocaine analogs where the aromatic ring of the lidocaine molecule is replaced with a cluster boron group. The invention also provides methods for making the cluster boron compounds comprising contacting a halogenated cluster boron with an amino acetamide in the presence of a catalyst, a proton acceptor, and a ligand.


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