The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2015

Filed:

Dec. 18, 2012
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Benjamin Fauber, San Francisco, CA (US);

Olivier Rene, San Francisco, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/495 (2006.01); A61K 31/496 (2006.01); C07D 295/26 (2006.01); C07D 295/135 (2006.01); C07D 295/185 (2006.01); C07C 311/13 (2006.01); C07D 491/107 (2006.01); C07D 309/14 (2006.01); C07D 405/04 (2006.01); C07D 241/08 (2006.01); C07D 241/04 (2006.01); C07D 471/08 (2006.01); C07D 471/10 (2006.01); C07D 487/08 (2006.01); C07D 487/10 (2006.01); C07D 207/12 (2006.01); C07D 207/14 (2006.01); C07D 211/46 (2006.01); C07D 211/58 (2006.01); C07D 305/06 (2006.01); C07D 305/08 (2006.01); C07D 265/30 (2006.01); C07D 267/14 (2006.01); C07C 311/10 (2006.01);
U.S. Cl.
CPC ...
C07D 491/107 (2013.01); C07C 311/13 (2013.01); C07D 207/12 (2013.01); C07D 207/14 (2013.01); C07D 211/46 (2013.01); C07D 211/58 (2013.01); C07D 241/04 (2013.01); C07D 241/08 (2013.01); C07D 265/30 (2013.01); C07D 267/14 (2013.01); C07D 295/135 (2013.01); C07D 295/185 (2013.01); C07D 295/26 (2013.01); C07D 305/06 (2013.01); C07D 305/08 (2013.01); C07D 309/14 (2013.01); C07D 405/04 (2013.01); C07D 471/08 (2013.01); C07D 471/10 (2013.01); C07D 487/08 (2013.01); C07D 487/10 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01);
Abstract

Compounds of the formula I: or pharmaceutically acceptable salts thereof,wherein m, n, A, X, X, X, X, R, R, R, R, Rand Rare as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.


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