The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2015

Filed:

Nov. 25, 2011
Applicants:

Eun Kyong Shim, Gyeonggi-do, KR;

Nam Doo Kim, Incheon, KR;

Tae BO Shim, Seoul, KR;

Seung Yong Kim, Gyeonggi-do, KR;

Inventors:

Eun Kyong Shim, Gyeonggi-do, KR;

Nam Doo Kim, Incheon, KR;

Tae Bo Shim, Seoul, KR;

Seung Yong Kim, Gyeonggi-do, KR;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 473/00 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
C07D 473/00 (2013.01); C07D 401/04 (2013.01);
Abstract

A novel purinylpyridinylamino-2,4-difluorophenyl sulfonamide derivative, a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition with an inhibitory activity against Raf kinase, containing the same as an active ingredient are provided. The purinylpyridinylamino-2,4-difluorophenyl sulfonamide derivative of the present invention effectively regulates the activity of B-Raf kinase, and thus may be useful for preventing or treating cancers induced by the over-activation of Raf kinase, especially various melanoma, colorectal cancer, prostate cancer, thyroid cancer, ovarian cancer and the like.


Find Patent Forward Citations

Loading…