The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2015
Filed:
Dec. 16, 2014
Applicants:
The United States of America As Represented BY the Secretary of the Department of Health and Human Services, Washington, DC (US);
Istituto Superiore Di SanitĂ , Rome, IT;
Inventors:
Bo Peng, Rockville, MD (US);
Rebecca Voltan, Ferrara, IT;
Barbara Ensoli, Rome, IT;
Marjorie Robert-Guroff, Rockville, MD (US);
Assignees:
The United States of America as represented by the Secretary of the Department of Health and Human Services, Washington, DC (US);
Istituto Superiore di Sanita, Rome, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/21 (2006.01); C12N 7/00 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/21 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/575 (2013.01); C12N 2710/10043 (2013.01); C12N 2710/16143 (2013.01); C12N 2740/16034 (2013.01); C12N 2740/16071 (2013.01); C12N 2740/16234 (2013.01);
Abstract
This invention provides improved replication-competent adenoviral vectors. The improved vectors have both a hybrid regulatory unit that provides for high level transgene expression. The vectors can be use, e.g., for therapeutic or prophylactic purposes.