The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 22, 2015

Filed:

Oct. 01, 2012
Applicants:

Michael D. Altman, Needham, MA (US);

Corey E. Bienstock, Natick, MA (US);

John W. Butcher, Berlin, MA (US);

Kaleen Konrad Childers, Newton, MA (US);

Maria Emilia Di Francesco, Houston, TX (US);

Anthony Donofrio, Cambridge, MA (US);

John Michael Ellis, Needham, MA (US);

Christian Fischer, Natick, MA (US);

Andrew M. Haidle, Cambridge, MA (US);

James P. Jewell, Somerville, MA (US);

Sandra Lee Knowles, Princeton, NJ (US);

Alan B. Northrup, Reading, MA (US);

Ryan D. Otte, Natick, MA (US);

Scott L. Peterson, Salem, MA (US);

Graham Frank Smith, Sudbury, MA (US);

Inventors:

Michael D. Altman, Needham, MA (US);

Corey E. Bienstock, Natick, MA (US);

John W. Butcher, Berlin, MA (US);

Kaleen Konrad Childers, Newton, MA (US);

Maria Emilia Di Francesco, Houston, TX (US);

Anthony Donofrio, Cambridge, MA (US);

John Michael Ellis, Needham, MA (US);

Christian Fischer, Natick, MA (US);

Andrew M. Haidle, Cambridge, MA (US);

James P. Jewell, Somerville, MA (US);

Sandra Lee Knowles, Princeton, NJ (US);

Alan B. Northrup, Reading, MA (US);

Ryan D. Otte, Natick, MA (US);

Scott L. Peterson, Salem, MA (US);

Graham Frank Smith, Sudbury, MA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/73 (2006.01); A61K 31/4439 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 213/81 (2006.01); C07D 401/12 (2006.01); C07D 409/14 (2006.01); C07D 417/14 (2006.01); C07D 487/04 (2006.01); C07D 495/04 (2006.01); A61K 31/444 (2006.01); A61K 31/496 (2006.01); A61K 31/5025 (2006.01); A61K 31/506 (2006.01); A61K 31/519 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 31/444 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/5025 (2013.01); A61K 31/519 (2013.01); A61K 31/5377 (2013.01); C07D 213/81 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01);
Abstract

The invention provides certain 2-pyridyl carboxamide-containing compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.


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