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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9213031 B1

PDFFull Text
Date of Patent:
Dec. 15, 2015

Filed:

Jul. 23, 2013

Use of cbl as biomarker for identifying subject suitable for treatment with anti-c-met antibody

Applicant:

Samsung Electronics Co., Ltd., Suwon-si, Gyeonggi-do, KR;

Inventors:

Ji Min Lee, Seoul, KR;

Kyung Ah Kim, Seongnam-si, KR;

Bo Gyou Kim, Seoul, KR;

Young Mi Oh, Seoul, KR;

Saet Byoul Lee, Seoul, KR;

Yun Ju Jeong, Anyang-si, KR;

Assignee:

SAMSUNG ELECTRONICS CO., LTD., Suwon-Si, KR;

Attorney:

Leydig, Voit & Mayer, Ltd.

Primary Examiner:

Sean Aeder

Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/53 (2006.01); G01N 33/574 (2006.01); C07K 16/30 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57492 (2013.01); A61K 39/39558 (2013.01); C07K 16/2863 (2013.01); C07K 16/30 (2013.01); C12Q 1/6886 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01); G01N 2800/52 (2013.01);
Abstract

A method of identifying a cell sample or a subject suitable for treatment with an anti-c-Met antibody or antigen binding fragment thereof that specifically binds to an epitope within a SEMA domain of a c-Met protein by determining a Cbl concentration, a Cbl mutation, and/or a mutation of a site of c-Met for interaction with Cbl in a cell sample from a subject, as well as related compositions and methods.

Find Patent Forward Citations

Lee, Ji. (2015). Use of cbl as biomarker for identifying subject suitable for treatment with anti-c-met antibody (U.S. Patent No. 9213031). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9213031

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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