The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2015
Filed:
Dec. 19, 2014
Applicant:
The Ohio State University, Columbus, OH (US);
Inventor:
Carlo M. Croce, Columbus, OH (US);
Assignee:
The Ohio State University, Columbus, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12Q 1/68 (2006.01); A61K 38/19 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); A61K 38/191 (2013.01); C12Q 1/6876 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01);
Abstract
It is disclosed herein that miR-221 and miR-222 down-regulate PTEN and TIMP3 tumor suppressors, resulting in TRAIL resistance. The present invention provides research, diagnostic, and therapeutic tools and methods related to this discovery. Diagnostics, prognostics and treatments for human hepatocellular cancer and non-small cell lung carcinoma having a TRAIL resistance are particularly described herein.
Quick Actions:
Croce, Carlo. (2015). Materials and methods useful for affecting tumor cell growth, migration and invasion (U.S. Patent No. 9212396). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9212396
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