The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2015

Filed:

Oct. 24, 2012
Applicant:

Biogen Idec MA Inc., Cambridge, MA (US);

Inventors:

Valerie Liu Tsang, Carlsbad, CA (US);

Angela Xiaoying Wang, Cardiff by the Sea, CA (US);

Helena Yusuf-Makagiansar, San Diego, CA (US);

Assignee:

Biogen Idec MA Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/02 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); C07K 16/00 (2013.01); Y10T 436/115831 (2015.01); Y10T 436/116664 (2015.01); Y10T 436/117497 (2015.01); Y10T 436/12 (2015.01);
Abstract

The present invention pertains to methods of increasing the efficiency of producing a bioproduct. In some embodiments, the method increases the quantity of a bioproduct produced, or decreases bioproduct production time, in a bioreactor cell culture producing the bioproduct, the method comprising, (a) intermittently or continuously analyzing the concentration of one or more nutrients in the bioreactor cell culture; and (b) adding to the bioreactor cell culture additional nutrient media when the concentration of the one or more nutrients is lower than a target value.


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