The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2015

Filed:

Feb. 09, 2007
Applicants:

Thomas Paccalet, Rouen, FR;

Muriel Bardor, St. Martin l'Hortier, FR;

Christophe Rihouey, Sainte-Foy, CA;

Véronique Gomord, Rouen, FR;

Loïc Faye, Saint-Jacques-sur-Darnétal, FR;

Patrice Lerouge, Grand Couronne, FR;

Stéphanie Aquin, Chavannes, CH;

Louis-philippe Vezina, Neuville, CA;

Marc-andré D'aoust, Québec, CA;

Inventors:

Thomas Paccalet, Rouen, FR;

Muriel Bardor, St. Martin l'Hortier, FR;

Christophe Rihouey, Sainte-Foy, CA;

Véronique Gomord, Rouen, FR;

Loïc Faye, Saint-Jacques-sur-Darnétal, FR;

Patrice Lerouge, Grand Couronne, FR;

Stéphanie Aquin, Chavannes, CH;

Louis-Philippe Vezina, Neuville, CA;

Marc-André D'Aoust, Québec, CA;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C12N 9/88 (2006.01); C12P 19/26 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8257 (2013.01); C12N 9/88 (2013.01); C12N 15/8245 (2013.01); C12P 19/26 (2013.01); C12P 21/005 (2013.01);
Abstract

A method of synthesizing sialic acid in plants, and plants capable of synthesizing sialic acid is provided. Furthermore, a method of producing sialylated protein in a plant is also provided. The method to synthesize sialic acid comprises providing a plant comprising a nucleotide sequence encoding N-acetyl neuraminic acid (Neu5Ac) synthase or Neu5Ac lyase, and expressing the nucleotide sequence thereby synthesizing sialic acid. The plant may also co-express a nucleotide sequence encoding one or more than one of an epimerase, a CMP-Neu5 Ac synthase, a CMP-Neu5Ac transporter and a sialyltransferase.


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