The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 15, 2015
Filed:
Jun. 18, 2012
Applicants:
Robert A. Weinberg, Brookline, MA (US);
Sendurai A. Mani, Houston, TX (US);
Mai-jing Liao, Winchester, MA (US);
Inventors:
Robert A. Weinberg, Brookline, MA (US);
Sendurai A. Mani, Houston, TX (US);
Mai-Jing Liao, Winchester, MA (US);
Assignee:
WHITEHEAD INSTITUTE, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); C12N 5/10 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0631 (2013.01); C12N 2501/15 (2013.01); C12N 2501/60 (2013.01); C12N 2510/00 (2013.01);
Abstract
Methods for preparing progenitor cells are described where epithelial cells are induced to undergo epithelial-mesenchymal transition as a result of exposure to an inducing agent or introduction of a gene therein that induces epithelial-mesenchymal transition. Progenitor cells resulting therefrom have use in cell-based therapies, among other utilities.