The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 2015

Filed:

Oct. 04, 2011
Applicants:

Won Jong Kim, Gyeongsangbuk-do, KR;

Yanggy Lee, Gyeongsangnam-do, KR;

Kwideok Park, Seoul, KR;

Jihoon Kim, Gyeongsangbuk-do, KR;

Dong Keun Han, Seoul, KR;

Inventors:

Won Jong Kim, Gyeongsangbuk-do, KR;

Yanggy Lee, Gyeongsangnam-do, KR;

Kwideok Park, Seoul, KR;

Jihoon Kim, Gyeongsangbuk-do, KR;

Dong Keun Han, Seoul, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/34 (2006.01); A61L 27/34 (2006.01); C08L 71/02 (2006.01); C08G 73/02 (2006.01); A61L 27/54 (2006.01); C08G 63/685 (2006.01);
U.S. Cl.
CPC ...
C08G 73/024 (2013.01); A61L 27/34 (2013.01); A61L 27/54 (2013.01); C08G 63/6852 (2013.01); C08G 73/0206 (2013.01); C08L 71/02 (2013.01); A61K 47/34 (2013.01); A61L 2300/114 (2013.01);
Abstract

A donor capable of controlled release of nitric monoxide and a prosthetic implant whose surface is coated with this donor are disclosed. The donor comprises a main chain of an organic polymer and a side chain that is covalently linked to the main chain and has a diazeniumdiolate functional group. The donor for controlled release of nitric monoxide exists in a fluid state such as liquid at room temperature and undergoes a sol-to-gel phase transition at a physiological pH as the temperature increases above the critical temperature. The critical temperature of the phase transition is in the range of 25 to 35° C., and the gel is a hydrogel without chemical cross-links.


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